In the same section
- Female Fertility Projects
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Male Fertility Projects
- 1 The role of ion channels in spermatogenesis and the sperm capacitation process.
- 2.Mathematical modelling and experimental study of the sperm capacitation process
- 3.Impact of capacitation failure in human sperm and the identification of capacitation biomarkers in male infertility.
- 4.Pharmacological protection against chemotherapy damage
- Scientific Activities
- Médecine
- Human Reproduction
- EN
- Activities
- Female fertility
- Fundamental Research
- Breast cancer
Fertility preservation and Breast cancer
- Fertility preservation and Breast cancer
Young breast cancer patients represent around 40% of counseling for fertility preservation in our institution. Young breast cancer patients display unique features that should be taken into consideration during reproductive counseling. Considering the paucity of the data available on fertility preservation outcomes and Assisted Reproductive Therapy (ART) in breast cancer patients, the laboratory has developed different projects specifically addressing the issue of breast cancer patients. Ongoing study in human and mice also evaluated the safety and the efficiency of adapted ovarian stimulation protocol using letrozole for breast cancer patients in order to collect and vitrify oocytes by avoiding harmful effect of hormones on tumoral progression during treatment.
Recently, the lab is studying the impact of new anticancer treatments on the gonads, and more particularly for patients with a genetic mutation predisposing to breast cancer (BRCA) thanks to the transgenic animal model and the use of the ovarian tissue donated for the research